Negin Azadi Introduction

Negin cancer center is one of the finest and most modern centers in Iran which  provides innovative, high quality radiation treatment to patients in the safest possible manner

It offers extensive options for radiation therapy to treat cancers of the prostate, breast, brain, liver, pancreas, head and neck, bones, and lungs

Our radiation oncologists and radiation physicists develop plans for individualized treatment which provides top-ranked care and enhance health outcomes and our team of expert radiation oncologists, radiation therapists, dosimetrists, and physicists are committed to the quality of our care

Your care does not end when your treatment is over. Our cancer survivorship staff members help you cope with any side effects from the cancer and the cancer treatment

Department of radiation oncology

Department of radiation oncology has linacs delivery treatment with low- and high-energy photons and a range of electron energies. which  is equipped with the world’s most advanced megavoltage 3D imaging system the  megavoltage cone beam computed tomography (MVCT) for guiding patient positioning in complex cases

Our linear accelerators is also equipped with multileaf collimation, and quality control software to avoid treatment errors which improves targeting of the radiation beam and reduces risk to nearby tissue

We use an unflattened 7MV and flattened 6 and 15MV  photon beam operating a dose rates up to 2000cGy/minute to reduce the effect of patient, organ or tumor motion on the treatment delivery and plan

We  have adopted advanced techniques and technology, such as volumetric-modulated arc therapy (VMAT), and both intensity-modulated radiation therapy (IMRT) and image-guided radiation therapy (IGRT), to optimize treatment

3D conformal radiation therapy

This technique that uses three-dimensional scans to determine the exact shape and size of the tumor. The radiation beams are shaped by tiny metal leaves that are arranged to fit the tumor dimensions (multi-leaf collimator), minimizing the side effects to healthy tissue.

Three dimensional conformal radiation therapy (3DCRT) involves imaging, precise radiation dose calculation, computer optimized treatment planning, and computer controlled treatment delivery. Treatment plans for each patient are individually designed. Using our state of the art technology, we are able to merge the treatment planning CT scan with diagnostic quality images, such as MRI and PET scans, to maximize the precision of our tumor targeting.

Image guided radiation therapy (IGRT)

Image guidance is available on all of our radiation machines and includes X-rays, standard strength CT imaging built into radiation machines, and fully functional CT imaging scanners built into a treatment suite alongside the radiation machine. These imaging systems will track your tumor or implanted markers called fiducials during the course of radiation.

Image-Guided Radiation Therapy (IGRT) is one of the most advanced innovations in cancer technology available. There are many factors that may contribute to differences between the planned dose distribution and the delivered dose distribution. One such factor is uncertainty in patient position on the treatment unit. IGRT refers to the use of advanced imaging (2D and 3D) to assure that the positioning of the tumor will match the highly conformal dose delivery that can be achieved on state of the art machines.

Tumors can move during treatment because of breathing and other movement within the body. IGRT allows our doctors to locate and track the tumor during treatment. With this technology, we can deliver precise radiation treatment to tumors that shift because of breathing and movement of the bladder and bowels.

Intensity modulated radiation therapy (IMRT) 

IMRT focuses multiple radiation beams of different intensities directly on the tumor for the highest possible dose.

IMRT planning starts with tumor target and normal tissue definition, followed by inverse planning. Using computer optimization, multiple small fields are designed to give a complex and conformal radiation dose distribution, which provides the prescription dose to the tumor target and minimizes dose to regional normal tissues. IMRT has been widely accepted as an excellent treatment modality for many different tumor types. IMRT may improve cancer control rates and decrease toxicity rates in certain tumor types, such as head and neck cancer, prostate cancer, and some brain tumors.

Stereotactic radiosurgery (SRS) 

Stereotactic radiosurgery is not actually surgery. Instead, uses dozens of tiny radiation beams to treat tumors in the head and neck with a single radiation dose.

And involves the delivery of a high dose of radiation precisely focused on a target within the brain

Stereotactic body radiation therapy (SBRT) 

Stereotactic Body Radiation Therapy (SBRT) is a treatment procedure similar to stereotactic radiosurgery for the central nervous system, except that SBRT treats tumors outside of the central nervous system. A stereotactic radiation treatment for the body means that a specially designed coordinate-system is used for the exact localization of the tumors in the body in order to treat them with limited but highly precise treatment fields. SBRT involves the delivery of a single high dose radiation treatment, or a few fractionated radiation treatments (usually up to five treatments).

Volumetric modulated arc therapy (VMAT)

VMAT is a form of IMRT in which multiple radiation beams of different intensities are directed at the tumor through a rotating radiation treatment machine. As the machine rotates, radiation is delivered at every angle focusing the highest possible dose of radiation to the tumor while minimizing radiation to surrounding healthy organs.

Physics department

The Department of Radiation Physics provides safe, accurate and high quality patient care in collaboration with radiation oncologists its mission is to :

Provide quality assurance of imaging and treatment delivery equipment and to ensure optimal, accurate and safe delivery of treatments

Provide clinical services in support of imaging and planning, delivery and patient-specific quality assurance of radiation treatments

Provide patient specific consultations as requested by the oncologists

Ct simulation

Radiation therapy requires careful planning to ensure the tumor is targeted with the least amount of impact on surrounding tissues. CT scanners simulate treatments by testing various beam fields and immobilization devices used to keep the patient from moving during treatment. Data from the simulators help calculate the appropriate dose before treatment begins

Our CT simulation device  is a highly flexible, intuitive CT simulator. With fully integrated hardware and software tailored specifically to your requirements, it increases certainty and reduces the likelihood of errors. It also features advanced algorithms, AI-powered organ-at-risk (OAR) autocontouring, and excellent soft-tissue contrast potentially decreasing target margins.

Other abilities

Elimination of any metal artifacts creating high accuracy of medical calculations.

The diameter of the gantry opening is more than 80 cm, which allows the patient to undergo  a CT in its therapeutic position, which is especially important in breast cancer and in overweight patients.

Flat bed surface similar to the accelerators bed

The presence of external lasers which can increase the setup accuracy

Immobilization Equipment

To optimize radiotherapy delivery, it must be the aim to minimize margins as much as possible. This can be achieved by improving patient setup and immobilization providing reproducible patient positioning with minimal patient movement

Fortunately, our center has the most advanced immobilization devices for all types of tumors. Which reduces  the patients movement less than 1 mm.

Motion Management System Equipment

In the treatment of tumors in the chest and abdomen where involuntary breathing  leads to tumor movement, the presence of respiratory gating  system can synchronize the ionizing radiation with each respiratory phase, in other words, we can irradiate the tumor only in the inhalation or exhalation phase

Planning systems

We use tow types of planning systems :

RayStation : which is a novel treatment planning systems with features like multi-criteria optimization, ultrafast computation speed and 4D adaptive radiation therapy.

ISOgray : enables us to make ours  clinical decisions based on accurate dose calculations and plan the dose delivery with confidence

Dosimetry and Quality Control System

To ensure proper functioning of technical equipment producing ionizing radiation and to avoid unintended exposure , we check the radiation output quality after installation and frequently overtime

In our center calibration laboratory in hands of a experienced dosimeterist using equipment from  PTW company provides a correct measurement of radiation quantities

Accessibilities 

Negin cancer center is located in the center of the city which is surrounded by lots of high quality hotels for your stay

Easy access to public transportation including taxi and bus and only a three minute walk from Tohids subway station is another advantage of our center

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